Article
Reconstructing the epidemic history of HIV-1 circulating recombinant forms CRF07_BC and CRF08_BC in East Asia: the relevance of genetic diversity and phylodynamics for vaccine strategies.
Vaccine - 26 May 2010
Takebe Yutaka, Liao Huanan, Hase Saiki, Uenishi Rie, Li Yue, Li Xiao-Jie, Han Xiaoxu, Shang Hong, Kamarulzaman Adeeba, Yamamoto Naoki, Pybus Oliver G, Tee Kok Keng
Abstract excerpt
HIV-1 CRF07_BC and CRF08_BC are closely related circulating recombinant forms (CRFs) with serious public health consequences in China. The temporal and spatial dynamics of these CRFs were determined by estimating their times of divergence, using phylogenetic and Bayesian coalescent methods. Studies of the timelines of CRF07_BC and CRF08_BC trace the expansion of these strains back their origins to Yunnan...
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