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Article

Motor uncoordination and neuropathology in a transgenic mouse model of Machado–Joseph disease lacking intranuclear inclusions and ataxin-3 cleavage products

26 May 2010

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PMID: 20510362
DOI: 10.1016/j.nbd.2010.05.021

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Motor uncoordination and neuropathology in a transgenic mouse model of Machado–Joseph disease lacking intranuclear inclusions and ataxin-3 cleavage productsPMID 20510362Read ↗

Striatal and nigral pathology in a lentiviral rat model of Machado-Joseph diseaseSemantic proximity Read ↗

Polyglutamine diseases: The special case of ataxin-3 and Machado–Joseph diseaseSemantic proximity Read ↗

Mitochondrial dysfunction in Machado Joseph Disease: insights from a multi-model systemSemantic proximity Read ↗

Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado-Joseph disease.Semantic proximity Read ↗

A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration.Semantic proximity Read ↗

Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado–Joseph diseaseSemantic proximity Read ↗

RNA Interference Mitigates Motor and Neuropathological Deficits in a Cerebellar Mouse Model of Machado-Joseph DiseaseSemantic proximity Read ↗

Machado Joseph disease: clinical and genetic aspects, and current treatmentSemantic proximity Read ↗

Selective occurrence of TDP-43-immunoreactive inclusions in the lower motor neurons in Machado–Joseph diseaseSemantic proximity Read ↗

Machado-Joseph Disease: from first descriptions to new perspectives.Semantic proximity Read ↗

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