Article
Gene expression profile in the salivary glands of primary Sjögren's syndrome patients before and after treatment with rituximab
13 Apr 2010
Abstract excerpt
OBJECTIVE: Primary Sjögren's syndrome (SS) is a complex disorder, in part due to B cell abnormalities. Although anti-B cell therapy is promising in primary SS, no treatment has yet been demonstrated to modify the disease course. This open-label study was undertaken to evaluate the efficacy of rituximab in primary SS and to investigate whether expression of specific genes is associated with efficacy of this...
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