Article
Association between genetic polymorphisms in fibroblast growth factor (FGF)1 and FGF2 and risk of endometriosis and adenomyosis in Chinese women.
Human reproduction (Oxford, England) - 1 Jul 2010
Kang Shan, Li Shi-Zhen, Wang Na, Zhou Rong-Miao, Wang Tao, Wang Dong-Jie, Li Xiao-Fei, Bui Jack, Li Yan
Abstract excerpt
BACKGROUND: Angiogenesis appears to be an important event in the pathophysiology of endometriosis (EM) and adenomyosis. Two angiogenic factors, fibroblast growth factor (FGF) 1 and 2, play a central role in the initiation of angiogenesis. We investigated whether FGF1 -1385A/G and FGF2 754C/G polymorphisms are associated with a risk of developing EM and adenomyosis. METHODS: Genotypes were analyzed by the...
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