Article
Polymorphisms in the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 and the risk of human adenomyosis.
Environmental and molecular mutagenesis - 1 Apr 2008
Kang Shan, Zhao Xiwa, Xing Huimin, Wang Na, Zhou Rongmiao, Chen Shucheng, Li Wansheng, Zhao Jian, Duan Yanan, Sun Donglan, Li Yan
Abstract excerpt
The matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) may contribute to the development of adenomyosis. The aim of the present study was to investigate whether three single nucleotide polymorphisms (SNPs) in the promoter regions of MMP-2 (-1306C/T and -735C/T) and TIMP-2 (-418G/C) genes were related to the risk of adenomyosis development. Genotypes were determined by polymerase...
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