Article
Obesity and polycystic ovary syndrome: association with androgens, leptin and its genotypes.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Dec 2010
Pusalkar Madhavi, Meherji Pervin, Gokral Jyotsna, Savardekar Lalita, Chinnaraj Saravanan, Maitra Anurupa
Abstract excerpt
Obesity and hyperandrogenaemia are key features of polycystic ovary syndrome (PCOS). The aim of this study was to investigate whether leptin and androgens are associated with obesity in PCOS subjects and identify whether there exist any genetic alterations in leptin gene in women with PCOS. The results reveal that leptin levels are elevated in women with PCOS and associate with BMI. However, irrespective of the...
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