Article
Genetic variation of CHRNA4 does not modulate attention in Parkinson's disease.
Neuroscience letters - 26 Jul 2010
Hudson Gavin, Stutt Andrea, Eccles Martin, Robinson Louise, Allcock Liesl M, Wesnes Keith A, Chinnery Patrick F, Burn David J
Abstract excerpt
Parkinson's disease (PD) is a neurodegenerative disorder, characterised by cognitive decline and attentional impairment. Recently, variation in CHRNA4 (rs1044396) has been shown to affect visual and auditory function, affecting speed and attention, in healthy adults. An association between CHRNA4 variation and PD has not been shown. To determine the link between CHRNA4 variation and attentional deficit in PD. A...
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