Article
IL-2 and IL-10 gene polymorphisms are associated with respiratory tract infection and may modulate the effect of vitamin E on lower respiratory tract infections in elderly nursing home residents.
The American journal of clinical nutrition - 1 Jul 2010
Belisle Sarah E, Hamer Davidson H, Leka Lynette S, Dallal Gerard E, Delgado-Lista Javier, Fine Basil C, Jacques Paul F, Ordovas Jose M, Meydani Simin Nikbin
Abstract excerpt
BACKGROUND: Vitamin E supplementation may be a potential strategy to prevent respiratory tract infections (RIs) in the elderly. The efficacy of vitamin E supplementation may depend on individual factors including specific single nucleotide polymorphisms (SNPs) at immunoregulatory genes. OBJECTIVE: We examined whether the effect of vitamin E on RIs in the elderly was dependent on genetic backgrounds as indicated...
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