Article
Risk of lower respiratory tract infections: a genome-wide association study with Mendelian randomization analysis in three independent European populations.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 May 2022
Flatby Helene M, Rasheed Humaira, Ravi Anuradha, Thomas Laurent F, Liyanarachi Kristin V, Afset Jan E, DeWan Andrew T, Brumpton Ben M, Hveem Kristian, Åsvold Bjørn O, Simonsen Gunnar S, Furberg Anne-Sofie, Damås Jan K, Solligård Erik, Rogne Tormod
Abstract excerpt
OBJECTIVE: Lower respiratory tract infections (LRTIs) are a leading cause of morbidity and mortality worldwide. Few studies have previously investigated genetic susceptibility and potential risk factors for LRTI. METHODS: We used data from the UK Biobank, Trøndelag Health Study (HUNT), and FinnGen to conduct a genome-wide association study (GWAS). Cases were subjects hospitalized with LRTI, and controls were...
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