Article
The cyclic AMP (cAMP)-cAMP receptor protein signaling system mediates resistance of Vibrio cholerae O1 strains to multiple environmental bacteriophages.
Applied and environmental microbiology - 1 Jul 2010
Zahid M Shamim Hasan, Waise T M Zaved, Kamruzzaman M, Ghosh Amar N, Nair G Balakrish, Mekalanos John J, Faruque Shah M
Abstract excerpt
Toxigenic Vibrio cholerae, the causative agent of the epidemic diarrheal disease cholera, interacts with diverse environmental bacteriophages. These interactions promote genetic diversity or cause selective enrichment of phage-resistant bacterial clones. To identify bacterial genes involved in mediating the phage-resistant phenotype, we screened a transposon insertion library of V. cholerae O1 El Tor biotype...
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