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Article

Metabolic effects of influenza virus infection in cultured animal cells: Intra- and extracellular metabolite profiling

13 May 2010

Abstract excerpt

BACKGROUND: Many details in cell culture-derived influenza vaccine production are still poorly understood and approaches for process optimization mainly remain empirical. More insights on mammalian cell metabolism after a viral infection could give hints on limitations and cell-specific virus production capacities. A detailed metabolic characterization of an influenza infected adherent cell line (MDCK) was...

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PMID: 20465796
DOI: 10.1186/1752-0509-4-61

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