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Article

Physiology and molecular genetics of poly(beta-hydroxy-alkanoic acid) synthesis in Alcaligenes eutrophus.

Molecular microbiology - 1 Mar 1991

Steinbüchel A, Schlegel H G

Abstract excerpt

The Alcaligenes eutrophus genes for beta-ketothiolase, NADPH-dependent acetoacetyl-CoA reductase and poly(beta-hydroxybutyric acid) synthase (PHB synthase) which comprise the three-step PHB-biosynthetic pathway, were cloned. Molecular studies revealed that these genes are organized in a single operon. The A. eutrophus PHB-biosynthetic genes are readily expressed in other bacteria, and DNA fragments harbouring the...

Topics

Acetyl-CoA C-Acyltransferase
Acyltransferases
Alcaligenes
Alcohol Oxidoreductases
Base Sequence
Gene Expression Regulation, Bacterial
Hydroxy Acids
Hydroxybutyrates
Molecular Sequence Data
Mutation
Operon

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Identifiers

PMID: 2046547
DOI: 10.1111/j.1365-2958.1991.tb00725.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2046547-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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