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Mitochondria Dysfunction and Neurodegenerative Disorders: Cause or Consequence

3 Jun 2010

Abstract excerpt

Mitochondria are crucial regulators of energy metabolism and apoptotic pathways and have been closely linked to the pathogenesis of neurodegenerative disorders. In this review we mainly focus on mitochondrial dysfunction in two of the most prevalent neurological disorders: Alzheimer's disease and Parkinson's disease. We discuss whether the role of mitochondria in those diseases should be considered primordial or...

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Identifiers

PMID: 20463408
DOI: 10.3233/jad-2010-100345

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