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Article

Rethinking the Relationship Between Hyperactivation and Chemotaxis in Mammalian Sperm1

13 May 2010

Abstract excerpt

Hyperactivation, a motility pattern of mammalian sperm in the oviduct, is essential to fertilization. Hyperactivation helps sperm to swim effectively through oviductal mucus, to escape from the sperm reservoir, and to penetrate the cumulus matrix and zona pellucida of the oocyte. There is some evidence that mammalian sperm can undergo chemotaxis; however, the relationship of chemotaxis to hyperactivation is...

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PMID: 20463353
DOI: 10.1095/biolreprod.109.083113

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