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Article

Oocyte‐type linker histone B4 is required for transdifferentiation of somatic cells in vivo

11 May 2010

Abstract excerpt

ABSTRACT The ability to reprogram in vivo a somatic cell after differentiation is quite limited. One of the most impressive examples of such a process is transdifferentiation of pigmented epithelial cells (PECs) to lens cells during lens regeneration in newts. However, very little is known of the molecular events that allow newt cells to transdifferentiate. Histone B4 is an oocyte‐type linker histone that...

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PMID: 20460584
DOI: 10.1096/fj.10-159285

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