Article
Chemical sensing in mammalian host-bacterial commensal associations.
Proceedings of the National Academy of Sciences of the United States of America - 25 May 2010
Hughes David T, Terekhova Darya A, Liou Linda, Hovde Carolyn J, Sahl Jason W, Patankar Arati V, Gonzalez Juan E, Edrington Thomas S, Rasko David A, Sperandio Vanessa
Abstract excerpt
The mammalian gastrointestinal (GI) tract is colonized by a complex consortium of bacterial species. Bacteria engage in chemical signaling to coordinate population-wide behavior. However, it is unclear if chemical sensing plays a role in establishing mammalian host-bacterial commensal relationships. Enterohemorrhagic Escherichia coli (EHEC) is a deadly human pathogen but is a member of the GI flora in cattle, its...
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