Article
Some consequences of demographic stochasticity in population genetics.
Genetics - 1 Aug 2010
Parsons Todd L, Quince Christopher, Plotkin Joshua B
Abstract excerpt
Much of population genetics is based on the diffusion limit of the Wright-Fisher model, which assumes a fixed population size. This assumption is violated in most natural populations, particularly for microbes. Here we study a more realistic model that decouples birth and death events and allows for a stochastically varying population size. Under this model, classical quantities such as the probability of and...
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