Article
The tight relationship between papillary thyroid cancer, autoimmunity and inflammation: clinical and molecular studies.
Clinical endocrinology - 1 May 2010
Muzza Marina, Degl'Innocenti Debora, Colombo Carla, Perrino Michela, Ravasi Elena, Rossi Stefania, Cirello Valentina, Beck-Peccoz Paolo, Borrello Maria Grazia, Fugazzola Laura
Abstract excerpt
OBJECTIVE: The recent concept that oncogenes responsible for thyroid neoplastic transformation are able to elicit an inflammatory protumourigenic microenvironment raises interest in further studies on papillary thyroid cancer (PTC) associated with thyroid autoimmunity. PATIENTS: The clinical and molecular features, and the expression of inflammation-related genes, were investigated in a large series of PTCs with...
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