Article
Desmin mutations as a cause of right ventricular heart failure affect the intercalated disks.
Heart rhythm - 1 Aug 2010
Otten Ellen, Asimaki Angeliki, Maass Alexander, van Langen Irene M, van der Wal Allard, de Jonge Nicolaas, van den Berg Maarten P, Saffitz Jeffrey E, Wilde Arthur A M, Jongbloed Jan D H, van Tintelen J Peter
Abstract excerpt
BACKGROUND: Mutations in the gene encoding desmin (DES), an intermediate filament protein, underlie a heterogeneous phenotype, which is referred to as desmin-related myopathy (DRM). Right ventricular involvement including an arrhythmogenic right ventricular cardiomyopathy (ARVC)(-like) phenotype...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.