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Article

RNA interference modulates replication of dengue virus in Drosophila melanogaster cells

1 Jan 2010

Abstract excerpt

BACKGROUND: Mosquito-borne dengue virus (DENV, genus Flavivirus) has emerged as a major threat to global human health in recent decades, and novel strategies to contain the escalating dengue fever pandemic are urgently needed. RNA interference (RNAi) induced by exogenous small interfering RNAs (siRNAs) has shown promise for treatment of flavivirus infections in hosts and prevention of transmission by vectors....

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PMID: 20420715
DOI: 10.1186/1471-2180-10-127

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