Article
Diverse pathways generate microRNA-like RNAs and Dicer-independent small interfering RNAs in fungi.
Molecular cell - 25 Jun 2010
Lee Heng-Chi, Li Liande, Gu Weifeng, Xue Zhihong, Crosthwaite Susan K, Pertsemlidis Alexander, Lewis Zachary A, Freitag Michael, Selker Eric U, Mello Craig C, Liu Yi
Abstract excerpt
A variety of small RNAs, including the Dicer-dependent miRNAs and the Dicer-independent Piwi-interacting RNAs, associate with Argonaute family proteins to regulate gene expression in diverse cellular processes. These two species of small RNA have not been found in fungi. Here, by analyzing small RNAs associated with the Neurospora Argonaute protein QDE-2, we show that diverse pathways generate miRNA-like small...
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