Article
Pregnancy and childbirth in carriers of the lamin A/C-gene mutation.
European journal of heart failure - 1 Jun 2010
Palojoki Eeva, Kaartinen Maija, Kaaja Risto, Reissell Eeva, Kärkkäinen Satu, Kuusisto Johanna, Heliö Tiina
Abstract excerpt
This retrospective case report describes 11 pregnancies in five women. All of the women were carriers of the lamin A/C gene mutation known to cause dilated cardiomyopathy, often together with atrioventricular conduction disturbances. The penetrance of these mutations is age-dependent but almost complete. We found no major adverse effects or worsening in the cardiac condition during or after the pregnancy in these...
Topics
- Adult
- Cardiomyopathy, Dilated
- Female
- Humans
- Lamin Type A
- Middle Aged
- Mutation
- Pregnancy
- Pregnancy Complications, Cardiovascular
- Retrospective Studies