Article
Genome-wide screen for individual identification SNPs (IISNPs) and the confirmation of six of them in Han Chinese with pyrosequencing technology.
Journal of forensic sciences - 1 Jul 2010
Zeng Zhaoshu, Yan Hongtao, Wang Li, Yuan Enwu, Yang Weihong, Liao Zhigang, Dong Ziming
Abstract excerpt
Single nucleotide polymorphisms (SNPs) offer promise to forensic DNA analysts, but it remains uncertain whether a panel of individual identification SNPs can be as informative as the Combined DNA Index System short tandem repeats. Based on the highly accurate and publicly available HapMap SNP database (r21a) and a minor allele frequency cutoff of >or=0.45, we completed a genome-wide screen through 3,905,819 SNPs...
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