Article
Fibroblast growth factor receptor 3 mutation analysis on voided urine for surveillance of patients with low-grade non-muscle-invasive bladder cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2010
Zuiverloon Tahlita C M, van der Aa Madelon N M, van der Kwast Theo H, Steyerberg Ewout W, Lingsma Hester F, Bangma Chris H, Zwarthoff Ellen C
Abstract excerpt
PURPOSE: Mutations in the fibroblast growth factor receptor 3 (FGFR3) have been found in 70% of the low-grade non-muscle-invasive bladder cancer (NMI-BC) tumors. We aim to determine the potential of FGFR3 mutation analysis on voided urine to detect recurrences during surveillance of patients with low-grade NMI-BC. EXPERIMENTAL DESIGN: FGFR3 mutation status of the study inclusion tumor was determined from 200...
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