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Early host responses to avian influenza A virus are prolonged and enhanced at transcriptional level depending on maturation of the immune system

11 Apr 2010

Abstract excerpt

Newly hatched chickens are more susceptible to infectious diseases than older birds because of an immature immune system. The aim of this study was to determine to what extent host responses to avian influenza virus (AIV) inoculation are affected by age. Therefore, 1- and 4-week (wk) old birds were inoculated with H9N2 AIV or saline. The trachea and lung were sampled at 0, 8, 16 and 24h post-inoculation (h.p.i.)...

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PMID: 20382427
DOI: 10.1016/j.molimm.2010.03.008

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