Article
Arabidopsis stromal-derived Factor2 (SDF2) is a crucial target of the unfolded protein response in the endoplasmic reticulum.
The Journal of biological chemistry - 4 Jun 2010
Schott Andrea, Ravaud Stéphanie, Keller Sabrina, Radzimanowski Jens, Viotti Corrado, Hillmer Stefan, Sinning Irmgard, Strahl Sabine
Abstract excerpt
Stresses increasing the load of unfolded proteins that enter the endoplasmic reticulum (ER) trigger a protective response termed the unfolded protein response (UPR). Stromal cell-derived factor2 (SDF2)-type proteins are highly conserved throughout the plant and animal kingdoms. In this study we have characterized AtSDF2 as crucial component of the UPR in Arabidopsis thaliana. Using a combination of biochemical...
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