Article
Programmed cell death regulator BAP2 is required for IRE1-mediated unfolded protein response in Arabidopsis.
Nature communications - 10 Jul 2024
Pastor-Cantizano Noelia, Angelos Evan R, Ruberti Cristina, Jiang Tao, Weng Xiaoyu, Reagan Brandon C, Haque Taslima, Juenger Thomas E, Brandizzi Federica
Abstract excerpt
Environmental and physiological situations can challenge the balance between protein synthesis and folding capacity of the endoplasmic reticulum (ER) and cause ER stress, a potentially lethal condition. The unfolded protein response (UPR) restores ER homeostasis or actuates programmed cell death (PCD) when ER stress is unresolved. The cell fate determination mechanisms of the UPR are not well understood,...
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