Intermediate alpha 1-antitrypsin deficiency with apical lung bullae and spontaneous pneumothorax. Presence of a Z variant in an American black.

doi:10.1378/chest.99.6.1545

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Intermediate alpha 1-antitrypsin deficiency with apical lung bullae and spontaneous pneumothorax. Presence of a Z variant in an American black.

Chest - 1 Jun 1991

Mostafavi S, Lieberman J

Abstract excerpt

A 43-year-old black man had an 18-year history of apical lung cystic-bullous disease. Following two episodes of spontaneous pneumothorax and two instances of thoracotomy for bullectomy and pleural abrasion, he was found to have an intermediate AAT deficiency with an MZ phenotype. It is believed that this is the first case of localized bullous lung disease to be reported in association with any degree of AAT...

Topics

Adult
Black People
Blister
Heterozygote
Humans
Lung
Lung Diseases
Male
Phenotype
Pneumothorax
Radiography
alpha 1-Antitrypsin

alpha 1-Antitrypsin Deficiency

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