Article
Differential regulation of dopaminergic gene expression by Er81.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 31 Mar 2010
Cave John W, Akiba Yosuke, Banerjee Kasturi, Bhosle Shivraj, Berlin Roseann, Baker Harriet
Abstract excerpt
A recent study proposed that differentiation of dopaminergic neurons requires a conserved "dopamine motif" (DA-motif) that functions as a binding site for ETS DNA binding domain transcription factors. In the mammalian olfactory bulb (OB), the expression of a set of five genes [including tyrosine hydroxylase (Th)] that are necessary for differentiation of dopaminergic neurons was suggested to be regulated by the...
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