Crystal-storing histiocytosis with renal Fanconi syndrome: pathological and molecular characteristics compared with classical myeloma-associated Fanconi syndrome.

doi:10.1093/ndt/gfq129

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Crystal-storing histiocytosis with renal Fanconi syndrome: pathological and molecular characteristics compared with classical myeloma-associated Fanconi syndrome.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Sept 2010

El Hamel Chahrazed, Thierry Antoine, Trouillas Patrick, Bridoux Frank, Carrion Claire, Quellard Nathalie, Goujon Jean-Michel, Aldigier Jean-Claude, Gombert Jean-Marc, Cogné Michel, Touchard Guy

Abstract excerpt

BACKGROUND: Crystal-storing histiocytosis (CSH) is a poorly described complication of monoclonal gammopathy featuring histiocyte lysosomal storage of kappa light chain (kappa LC) crystals. Although CSH is usually associated with systemic manifestations, renal involvement is uncommon. METHODS: To investigate the molecular mechanisms implicated in kappa LC crystallization, we performed immunopathological and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Crystallization

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fanconi Syndrome

Share to Immunoglobulin kappa-Chains

Share to Immunoglobulin Light Chains

Share to Kidney Diseases

Share to Models, Molecular

Share to Multiple Myeloma

Share to Sequence Homology, Amino Acid

Source

Open in PubMed

Identifiers

PMID: 20356978
DOI: 10.1093/ndt/gfq129

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Crystal-storing histiocytosis with renal Fanconi syndrome: pathological and molecular characteristics compared with classical myeloma-associated Fanconi syndrome.PMID 20356978Read ↗

Mutational Analysis in Murine Models for Myeloma-Associated Fanconi’s Syndrome or Cast Myeloma NephropathySemantic proximity Read ↗

Role of the monoclonal chain V domain and reversibility of renal damage in a transgenic model of acquired Fanconi syndromeSemantic proximity Read ↗

Crystal nephropathy: a variant form of myeloma kidney--a case report and review of the literature.Semantic proximity Read ↗

Extensive plasma cell infiltration with crystal IgG inclusions and mutated IgV(H) gene in an osteoarthritis patient with lymphoplasmacellular synovitis. A case report.Semantic proximity Read ↗

Somatic mutations of the L12a gene in V-kappa(1) light chain deposition disease: potential effects on aberrant protein conformation and deposition.Semantic proximity Read ↗

Multicentric Carpotarsal Osteolysis Syndrome Associated Nephropathy: Novel Variants of MAFB Gene and Literature ReviewSemantic proximity Read ↗

Causes of alternative pathway dysregulation in dense deposit disease.Semantic proximity Read ↗

Acquired and genetic determinants of disease phenotype and therapeutic strategies in C3 glomerulopathy and immunoglobulin-associated MPGNSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.