Article
Isolation, polymorphism and expression study of two distinct major histocompatibility complex class II B genes from half-smooth tongue sole (Cynoglossus semilaevis).
International journal of immunogenetics - 1 Jun 2010
Li C, Yu Y, Sun Y, Li S, Zhong Q, Wang X, Wang Z, Qi J, Zhang Q
Abstract excerpt
Major histocompatibility complex (MHC) class II antigens are important in vertebrate immune system, which present peptides to CD4(+) T cells. In the present study, cDNAs encoding MHC class II B gene were isolated from the cDNA library of half-smooth tongue sole (Cynoglossus semilaevis), and the full length cDNA sequences were got by rapid amplification of cDNA ends polymerase chain reaction. The polymorphism of...
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