Article
Mapping of three novel loci for non-syndromic autosomal recessive mental retardation (NS-ARMR) in consanguineous families from Pakistan.
Clinical genetics - 1 Nov 2010
Rafiq M A, Ansar M, Marshall C R, Noor A, Shaheen N, Mowjoodi A, Khan M A, Ali G, Amin-ud-Din M, Feuk L, Vincent J B, Scherer S W
Abstract excerpt
To date, of 13 loci with linkage to non-syndromic autosomal recessive mental retardation (NS-ARMR), only six genes have been established with associated mutations. Here we present our study on NS-ARMR among the Pakistani population, where people are traditionally bound to marry within the family or the wider clan. In an exceptional, far-reaching genetic survey we have collected more than 50 consanguineous...
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