Article
GB virus C quasispecies detected in plasma and lymphocyte subsets in a natural human infection.
The Journal of general virology - 1 Jul 2010
Ruiz Vanesa, Giordano Mirta, Rivero Cintia W, Minassian María L, Cuestas María L, Trinks Julieta, Mathet Verónica L, Oubiña José Raúl
Abstract excerpt
Genomic heterogeneity and quasispecies composition of GB virus C (GBV-C) within plasma and lymphocyte subsets in a naturally infected blood donor were investigated. For this purpose, fragments from the 5' untranslated region (5' UTR) and the E2 gene recovered from plasma, B and T lymphocytes, were cloned and sequenced. A total of 63 clones was analysed: 95.2 % of them (n=60) - obtained from plasma and cells -...
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