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Article

Sequence heterogeneity within the 5'-terminal region of the hepatitis GB virus C genome and evidence for genotypes.

Journal of hepatology - 1 Sept 1996

Muerhoff A S, Simons J N, Leary T P, Erker J C, Chalmers M L, Pilot-Matias T J, Dawson G J, Desai S M, Mushahwar I K

Abstract excerpt

BACKGROUND: GB virus C is a positive-strand RNA virus that is associated with hepatitis in humans. GB virus C bears some resemblance to hepatitis C virus in its genomic sequence and organization. However, unlike hepatitis C virus, an open reading frame possessing a complete core protein was not identified in the original isolate. METHODS: To verify the sequence at the 5'-end of the GB virus C genome, we amplified...

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PMID: 8895018
DOI: 10.1016/s0168-8278(96)80125-5

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