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GB Virus C Replicates in Primary T and B Lymphocytes

3 Jan 2006

Abstract excerpt

GB virus C (GBV-C) infection is common in humans and may persist for decades, although most infected persons clear the virus and subsequently develop antibodies to the envelope glycoprotein. GBV-C replicates in peripheral blood mononuclear cells (PBMCs) and CD4(+) T lymphocytes in vitro, and depletion of CD4(+) T lymphocytes has been proposed as the reason for clearance of GBV-C among persons positive for human...

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PMID: 16388494
DOI: 10.1086/499435

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