Article
Different effects of PPARA, PPARG and ApoE SNPs on serum lipids in patients with coronary heart disease based on the presence of diabetes.
Gene - 1 Jul 2013
Yilmaz-Aydogan Hulya, Kurnaz Ozlem, Kucukhuseyin Ozlem, Akadam-Teker Basak, Kurt Ozlem, Eronat Allison Pinar, Tekeli Atike, Bugra Zehra, Ozturk Oguz
Abstract excerpt
BACKGROUND: The aim of this study was to investigate the individual or combined effects of PPARA-L162V, PPARG-C161T and APOE polymorphisms on hyperlipidemia in coronary heart disease (CHD) patients. METHODS: Our study included 223 patients with CHD (103 with type 2 diabetes (T2DM), 120 without diabetes) and 101 controls. All genotypes were determined by PCR-RFLP technique. RESULTS: Genotypic and allelic...
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