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Article

The epidemiology of CuZn-SOD mutations in Germany: a study of 217 families.

Journal of neurology - 1 Aug 2010

Rabe Malessa, Felbecker Ansgar, Waibel Stefan, Steinbach Peter, Winter Pia, Müller Ulrich, Ludolph Albert C

Abstract excerpt

We screened 217 patients from Germany (n = 213), Austria (n = 2) and Switzerland (n = 2) with a positive family history for amyotrophic lateral sclerosis (ALS) for mutations in the copper/zinc superoxide dismutase (SOD1) gene. We found that 13% of the families tested carried mutations. By analyzing inheritance, we detected a clear-cut co-segregation in 5 of the 28 families; however, in two families with an...

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Source

Identifiers

PMID: 20309572
DOI: 10.1007/s00415-010-5512-9

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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