Article
Regulation of hemagglutinin/protease expression by the VarS/VarA-CsrA/B/C/D system in Vibrio cholerae.
Microbial pathogenesis - 1 Jun 2010
Jang Jeyoun, Jung Kyung-Tae, Yoo Cheon-Kwon, Rhie Gi-Eun
Abstract excerpt
In this study, through the analysis of Vibrio cholerae 2740-80 mutant strains produced by the cholera toxin subunit B gene containing Mariner-based transposon, we found that disruption of the varS gene, a member of the recently reported sensory system VarS/VarA-CsrA/B/C/D, resulted in altered expression of hemagglutinin/protease A. To further investigate the connection between VarS and HapA, we generated an...
Topics
- Bacterial Proteins
- Biofilms
- Cholera Toxin
- Gene Expression Regulation, Bacterial
- Metalloendopeptidases
- Mutation
- Promoter Regions, Genetic
- Sigma Factor
- Vibrio cholerae
