A new approach for copy number estimation in polyploids.

Abstract excerpt

In polyploids, the copy number (or marker dosage) of a dominant marker is the number of copies of a dominant allele carried by a parent. It is estimated using a hypothesis testing procedure. This procedure, however, suffers from issues associated with multiple testing and assumes all chromosomes pair uniformly. In this paper, a new Bayesian approach is presented for estimating the copy number of a dominant marker...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Chromosomes
• Share to Gene Dosage
• Share to Genes, Dominant