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Article

Priors for genotyping polyploids.

Bioinformatics (Oxford, England) - 1 Mar 2020

Gerard David, Ferrão Luís Felipe Ventorim

Abstract excerpt

MOTIVATION: Empirical Bayes techniques to genotype polyploid organisms usually either (i) assume technical artifacts are known a priori or (ii) estimate technical artifacts simultaneously with the prior genotype distribution. Case (i) is unappealing as it places the onus on the researcher to estimate these artifacts, or to ensure that there are no systematic biases in the data. However, as we demonstrate with a...

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PMID: 32176767
DOI: 10.1093/bioinformatics/btz852

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