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Article

Differential expression of mRNAs encoding BMP/Smad pathway molecules in antral follicles of high- and low-fecundity Hu sheep.

Animal reproduction science - 1 Jul 2010

Xu Yefen, Li Erlin, Han Yedong, Chen Ling, Xie Zhuang

Abstract excerpt

The Hu sheep is world-famous for its hyper-prolificacy and the bone morphogenetic protein (BMP)/Smad pathway and several other closely related molecules (GDF9, TGF-betaRI) have been shown to have a close relationship with reproduction in sheep. In order to investigate the mechanism of high fecundity in Hu sheep and its relationship with the BMP/Smad pathway, 147 Hu sheep were blood sampled for detection of the...

Topics

Animals
Base Sequence
Bone Morphogenetic Protein Receptors, Type I
Bone Morphogenetic Proteins
DNA Mutational Analysis
Female
Fertility
Gene Expression Regulation
Growth Differentiation Factor 9
Infertility, Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Ovarian Follicle

Polymorphism, Restriction Fragment Length

RNA, Messenger

Receptors, Transforming Growth Factor beta

Sheep

Signal Transduction

Smad Proteins

Source

Identifiers

PMID: 20303683
DOI: 10.1016/j.anireprosci.2010.02.009

Genes

GDF9
BMP15
BMP4
BMP2
BMP6
BMP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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