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Article

Sperm FISH analysis in two healthy infertile brothers with t(15;18) unbalanced translocation: Implications for genetic counselling and reproductive management.

European journal of medical genetics - 1 Jan 2000

Leclercq Sandrine, Auger Jacques, Dupont Céline, Le Tessier Dominique, Lebbar Aziza, Baverel Françoise, Dupont Jean Michel, Eustache Florence

Abstract excerpt

Numerous studies have shown that balanced reciprocal or Robertsonian translocations and inversions are associated with reduced or absent sperm production. In contrast, a similar association has been rarely reported for unbalanced translocations. An unbalanced translocation, 45,XY,-15,der(18)t(15;18)(q11.2;q23), was found in two healthy infertile brothers who were referred to our hospital together with their...

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Share to Chromosome Segregation
Share to Chromosomes, Human, Pair 15

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Reproductive Techniques, Assisted

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Source

Identifiers

PMID: 20302980
DOI: 10.1016/j.ejmg.2010.03.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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