Article
Distinct clustering of point mutations in mitochondrial DNA among patients with mitochondrial encephalomyopathies and with Parkinson's disease.
Biochemical and biophysical research communications - 30 Apr 1991
Ozawa T, Tanaka M, Ino H, Ohno K, Sano T, Wada Y, Yoneda M, Tanno Y, Miyatake T, Tanaka T
Abstract excerpt
The total sequence data for mitochondrial DNA (mtDNA) revealed distinct clustering of point mutations (pms) in mtDNA among one patient with myoclonus epilepsy with ragged-red fibers (MERRF), two patients with Parkinson's disease (PD), two patients with mitochondrial myopathy, encephalopathy, lact...
Topics
- Adolescent
- Adult
- DNA, Mitochondrial
- Female
- Humans
- Male
- Middle Aged
- Mitochondria, Muscle
- Multigene Family
- Mutation
- Parkinson Disease
- Phylogeny