Article
Protection of photoreceptors in a mouse model of RP10.
Advances in experimental medicine and biology - 1 Jan 2010
Tam Lawrence C S, Kiang Anna-Sophia, Chadderton Naomi, Kenna Paul F, Campbell Matthew, Humphries Marian M, Farrar G Jane, Humphries Pete
Abstract excerpt
Recombinant adeno-associated viral (rAAV) vectors have recently been widely used for the delivery of therapeutic transgenes in preclinical and clinical studies for inherited retinal degenerative diseases. Interchanging capsid genes between different AAV serotypes has enabled selective delivery of transgene into specific cell type(s) of the retina. The RP10 form of autosomal dominant retinitis pigmentosa (adRP) is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
