Article
"Forward genetics" as a method to maximize power and cost-efficiency in studies of human complex traits.
Behavior genetics - 1 Jul 2010
Boks M P M, Derks E M, Dolan C V, Kahn R S, Ophoff R A
Abstract excerpt
There is increasing interest in methods to disentangle the relationship between genotype and (endo)phenotypes in human complex traits. We present a population-based method of increasing the power and cost-efficiency of studies by selecting random individuals with a particular genotype and then as...
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