Biology of peripheral inherited neuropathies: Schwann cell axonal interactions.

Abstract excerpt

Development and maintenance of PNS myelin depends on continual signaling from axons ensheathed by myelin. Recent advances have demonstrated the roles of neuregulin 1 type III, Erb2/3 and intracellular signal transduction pathways in inducing Schwann cell myelination. Alternatively, maintenance of myelinated axons depends on healthy myelinating Schwann cells. Axonal degeneration is a feature of virtually all...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Axons
• Share to Cell Communication
• Share to Genetic Diseases, Inborn