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Article

Raltegravir as functional monotherapy leads to virological failure and drug resistance in highly treatment-experienced HIV-infected patients.

Scandinavian journal of infectious diseases - 1 Jul 2010

Caby Fabienne, Valin Nadia, Marcelin Anne Genevieve, Schneider Luminata, Andrade Régis, Guiguet Marguerite, Tubiana Roland, Canestri Ana, Valantin Marc Antoine, Peytavin Gilles, Pacanowski Jérome, Morand-Joubert Laurence, Calvez Vincent, Girard Pierre Marie, Katlama Christine

Abstract excerpt

The objective of this study was to evaluate the development of resistance to raltegravir (RAL) in patients with viraemia between 40 and 400 copies/ml. All HIV-1-infected patients with multidrug-resistant virus, plasma HIV-1 RNA >1000 copies/ml and starting RAL were enrolled in this observational study and followed up until week 48. Sixty-seven patients with median plasma HIV-1 RNA at 4.3 log(10) copies/ml and CD4...

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Identifiers

PMID: 20222846
DOI: 10.3109/00365541003621502

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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