Article
One amino acid substitution in phytoene desaturase makes Chlorella zofingiensis resistant to norflurazon and enhances the biosynthesis of astaxanthin.
Planta - 1 Jun 2010
Liu Jin, Zhong Yujuan, Sun Zheng, Huang Junchao, Jiang Yue, Sandmann Gerhard, Chen Feng
Abstract excerpt
A stable Chlorella zofingiensis mutant (E17) produced by chemical mutagen was characterized with respect to growth, astaxanthin biosynthesis, and phytoene desaturation. The mutant E17 could grow well and produce normal levels of colored carotenoids in the presence of 0.25 microM norflurazon, in which the growth of wild type (WT) cells was greatly limited due to inhibited carotenoid formation. Induced by...
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