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Article

Intrahost Evolutionary Dynamics of Canine Influenza Virus in Naive and Partially Immune Dogs

11 Mar 2010

Abstract excerpt

The patterns and dynamics of evolution in acutely infecting viruses within individual hosts are largely unknown. To this end, we investigated the intrahost variation of canine influenza virus (CIV) during the course of experimental infections in naïve and partially immune dogs and in naturally infected dogs. Tracing sequence diversity in the gene encoding domain 1 of the hemagglutinin (HA1) protein over the time...

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PMID: 20219907
DOI: 10.1128/jvi.02469-09

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