Article
Altered expression of neuronal nitric oxide synthase in weaver mutant mice.
Brain research - 22 Apr 2010
Cavalcanti-Kwiatkoski Roberta, Raisman-Vozari Rita, Ginestet Laure, Del Bel Elaine
Abstract excerpt
The weaver mouse represents the only genetic animal model of gradual nigrostriatal dopaminergic neurodegeneration which is proposed as a pathophysiological phenotype of Parkinson's disease. The aim of the present study was to analyze the nitric oxide and dopaminergic systems in selected brain regions of homozygous weaver mice at different postnatal ages corresponding to specific stages of the dopamine loss....
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